First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain.
نویسندگان
چکیده
489 la exploración abdominal, fueron normales. La pierna izquierda estaba enrojecida, caliente, a tensión, edematosa, dolorosa a la movilización, con flictenas localizadas y pulsos distales presentes. a fin de poder instaurar una rápida y adecuada antibioterapia. Bacteraemic necrotizing fasciitis with compartment syndrome caused by non O-1 Vibrio cholera. Incidence of Vibrio cholerae and related vibrios in a coastal lagoon and seawater influenced by lake discharges along an annual cycle. Primer caso en Espã na de Klebsiella pneumoniae ST258 productora de KPC-2 resistente a colistina Dear Sir, The rapid spread of Klebsiella pneumoniae carbapenemases (KPCs) in the last years represents a serious public health threat. KPCs have a great potential for spread due to their location on mobile genetic elements that are horizontally transferred and associated with widespread clones. 1 Many KPC producing K. pneu-moniae isolates are associated to a single sequence type (ST)258, a clonal lineage that has been causing epidemics of great proportions in various regions of USA, Israel, Greece and recently in other European countries. 2,3 Organisms carrying carbapenemases usually harbours resistance determinants to other antimicrobials and consequently infections due to these pathogens are difficult to treat which results in high associated morbidity. 4,5 Table 1 Antibiotic susceptibilities (MICs, mg/L) of K. oxytoca and K. pneumoniae isolates harbouring KPCs.
منابع مشابه
KPC-producing Klebsiella pneumoniae, finally targeting Turkey
We report here the first identification of the worldwide spread of Klebsiella pneumoniae carbapenemase-2-producing and carbapenem-resistant K. pneumoniae clone ST258 in Turkey, a country where the distantly-related carbapenemase OXA-48 is known to be endemic. Worryingly, this isolate was also resistant to colistin, now considered to be the last-resort antibiotic for carbapenem-resistant isolates.
متن کاملIsolation of a Klebsiella pneumoniae Isolate of Sequence Type 258 Producing KPC-2 Carbapenemase in Korea
Carbapenem-resistant Klebsiella pneumoniae isolates producing K. pneumoniae carbapenemases (KPC) were first reported in the USA in 2001, and since then, this infection has been reported in Europe, Israel, South America, and China. In Korea, the first KPC-2-producing K. pneumoniae sequence type (ST) 11 strain was detected in 2010. We report the case of a patient with a urinary tract infection ca...
متن کاملOutbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals.
We report the first outbreak caused by colistin-resistant Klebsiella pneumoniae producing KPC-3 carbapenamase in two Italian hospitals. This spread occurred in 1 month, and was caused by eight colistin-resistant and carbapenem-resistant Klebsiella pneumoniae isolates from eight patients. A further three isolates were obtained from the intestinal tract and pharyngeal colonization. All isolates w...
متن کاملClonality and Resistome Analysis of KPC-Producing Klebsiella pneumoniae Strain Isolated in Korea Using Whole Genome Sequencing
We analyzed the whole genome sequence and resistome of the outbreak Klebsiella pneumoniae strain MP14 and compared it with those of K. pneumoniae carbapenemase- (KPC-) producing isolates that showed high similarity in the NCBI genome database. A KPC-2-producing multidrug-resistant (MDR) K. pneumoniae clinical isolate was obtained from a patient admitted to a Korean hospital in 2011. The strain ...
متن کاملDraft genome sequence of an extremely drug-resistant KPC-producing Klebsiella pneumoniae ST258 epidemic strain.
Extremely drug-resistant (XDR) Klebsiella pneumoniae carbapenemase-producing clone ST258 has rapidly disseminated worldwide. We report here the draft genome sequence of the K. pneumoniae ST258 XDR clinical strain from Israel.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Enfermedades infecciosas y microbiologia clinica
دوره 31 7 شماره
صفحات -
تاریخ انتشار 2013