First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain.

نویسندگان

  • Amparo Valentín-Martín
  • Aránzazu Valverde-De Francisco
  • Montserrat Bosque-Vall
  • Rafael Cantón-Moreno
چکیده

489 la exploración abdominal, fueron normales. La pierna izquierda estaba enrojecida, caliente, a tensión, edematosa, dolorosa a la movilización, con flictenas localizadas y pulsos distales presentes. a fin de poder instaurar una rápida y adecuada antibioterapia. Bacteraemic necrotizing fasciitis with compartment syndrome caused by non O-1 Vibrio cholera. Incidence of Vibrio cholerae and related vibrios in a coastal lagoon and seawater influenced by lake discharges along an annual cycle. Primer caso en Espã na de Klebsiella pneumoniae ST258 productora de KPC-2 resistente a colistina Dear Sir, The rapid spread of Klebsiella pneumoniae carbapenemases (KPCs) in the last years represents a serious public health threat. KPCs have a great potential for spread due to their location on mobile genetic elements that are horizontally transferred and associated with widespread clones. 1 Many KPC producing K. pneu-moniae isolates are associated to a single sequence type (ST)258, a clonal lineage that has been causing epidemics of great proportions in various regions of USA, Israel, Greece and recently in other European countries. 2,3 Organisms carrying carbapenemases usually harbours resistance determinants to other antimicrobials and consequently infections due to these pathogens are difficult to treat which results in high associated morbidity. 4,5 Table 1 Antibiotic susceptibilities (MICs, mg/L) of K. oxytoca and K. pneumoniae isolates harbouring KPCs.

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عنوان ژورنال:
  • Enfermedades infecciosas y microbiologia clinica

دوره 31 7  شماره 

صفحات  -

تاریخ انتشار 2013